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Mouse Anti-FCER2 Recombinant Antibody (CBXF-0456) (CBMAB-F2272-CQ)

This product is a mouse antibody that recognizes FCER2. The antibody CBXF-0456 can be used for immunoassay techniques such as: IHC-P, WB.
See all FCER2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0456
Antibody Isotype
IgG
Application
IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 30% glycerol
Preservative
0.01% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fc Fragment Of IgE Receptor II
Introduction
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
Fc Fragment Of IgE Receptor II; Fc Fragment Of IgE, Low Affinity II, Receptor For (CD23); Immunoglobulin E-Binding Factor; Lymphocyte IgE Receptor; Fc Epsilon Receptor II; Fc-Epsilon-RII; CD23 Antigen; BLAST-2; CLEC4J; CD23A;
Research Area
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Biological Process
Positive regulation of humoral immune response mediated by circulating immunoglobulin Source: Ensembl
Positive regulation of killing of cells of other organism Source: BHF-UCL
Positive regulation of nitric-oxide synthase activity Source: BHF-UCL
Positive regulation of nitric-oxide synthase biosynthetic process Source: BHF-UCL
Cellular Location
Cell membrane; Cell membrane; Secreted. Also exists as a soluble excreted form, sCD23.
Topology
Cytoplasmic: 1-21
Helical: 22-47
Extracellular: 48-321
PTM
N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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