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Mouse Anti-FCER2 Recombinant Antibody (CBYY-C2478) (CBMAB-C3918-YY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2478
Antibody Isotype
IgG3
Application
FC, IHC, IP

Basic Information

Specificity
Human
Antibody Isotype
IgG3
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
0.2 mg/mL
Preservative
PBS
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fc Fragment Of IgE Receptor II
Entrez Gene ID
2208
UniProt ID
P06734
Alternative Names
Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; Alpha (1,3) Fucosyltransferase, Myeloid-Specific; ELAM-1 Ligand Fucosyltransferase; ELAM Ligand Fucosyltransferase; Fucosyltransferase IV; FUC-TIV; FucT-IV; FCT3A; ELFT; Stage-Specific Embryonic Antigen 1;
Research Area
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Biological Process
Positive regulation of humoral immune response mediated by circulating immunoglobulin Source: Ensembl
Positive regulation of killing of cells of other organism Source: BHF-UCL
Positive regulation of nitric-oxide synthase activity Source: BHF-UCL
Positive regulation of nitric-oxide synthase biosynthetic process Source: BHF-UCL
Cellular Location
Cell membrane; Cell membrane; Secreted. Also exists as a soluble excreted form, sCD23.
Topology
Cytoplasmic: 1-21
Helical: 22-47
Extracellular: 48-321
PTM
N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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