Sign in or Register
  • Home
  • FCER2
  • Mouse Anti-FCER2 Recombinant Antibody (2L6)

Mouse Anti-FCER2 Recombinant Antibody (2L6) (CBMAB-C5319-LY)

See all FCER2 antibodies
Go to compare Compare Online Inquiry
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
2L6
Application
WB
Immunogen
Synthetic Peptide
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% Glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Fc Fragment Of IgE Receptor II
Introduction
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Entrez Gene ID
Human2208
Mouse14128
Rat171075
UniProt ID
HumanP06734
MouseP20693
RatQ63097
Research Area
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Biological Process
Positive regulation of humoral immune response mediated by circulating immunoglobulin Source: Ensembl
Positive regulation of killing of cells of other organism Source: BHF-UCL
Positive regulation of nitric-oxide synthase activity Source: BHF-UCL
Positive regulation of nitric-oxide synthase biosynthetic process Source: BHF-UCL
Cellular Location
Cell membrane; Cell membrane; Secreted. Also exists as a soluble excreted form, sCD23.
Topology
Cytoplasmic: 1-21
Helical: 22-47
Extracellular: 48-321
PTM
N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.

Du, L., Chen, W., Li, C., Cui, Y., & He, Z. (2022). RNF144B stimulates the proliferation and inhibits the apoptosis of human spermatogonial stem cells via the FCER2/NOTCH2/HES1 pathway and its abnormality is associated with azoospermia. Journal of Cellular Physiology, 237(9), 3565-3577.

Aranda, C. J., Gonzalez‐Kozlova, E., Saunders, S. P., Fernandes‐Braga, W., Ota, M., Narayanan, S., ... & Lafaille, M. A. C. D. (2022). IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases. Allergy.

Soares, P., Fidler, K., Felton, J., Jones, C. J., Tavendale, R., Hövels, A., ... & Mukhopadhyay, S. (2021). An FCER2 polymorphism is associated with increased oral leukotriene receptor antagonists and allergic rhinitis prescribing. Clinical and experimental allergy, 51(8), 1089-1092.

Duong-Quy, S., Le-Thi-Minh, H., Nguyen-Thi-Bich, H., Pham-Thu, H., Thom, V. T., Pham-Thi-Hong, N., ... & Craig, T. J. (2020). Correlations between exhaled nitric oxide, rs28364072 polymorphism of FCER2 gene, asthma control, and inhaled corticosteroid responsiveness in children with asthma. Journal of breath research, 15(1), 016012.

Karimi, L., Vijverberg, S. J., Farzan, N., Ghanbari, M., Verhamme, K. M., & Maitland‐van der Zee, A. H. (2019). FCER2 T2206C variant associated with FENO levels in asthmatic children using inhaled corticosteroids: The PACMAN study. Clinical & Experimental Allergy, 49(11), 1429-1436.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-FCER2 Recombinant Antibody (2L6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

FCER2 Matched Antibody Pair (417) (CAT#: APMAB-417LY)

Related Products

Mouse Anti-FCER2 Recombinant Antibody (CBXF-0452) (CAT#: CBMAB-F0372-CQ)

Mouse Anti-FCER2 Recombinant Antibody (CBXC-0975) (CAT#: CBMAB-C1237-CQ)

Rabbit Anti-FCER2 Recombinant Antibody (7) (CAT#: CBMAB-C8387-LY)

Rabbit Anti-FCER2 Recombinant Antibody (CBYY-C2479) (CAT#: CBMAB-C3919-YY)

Mouse Anti-FCER2 Recombinant Antibody (0.N.92) (CAT#: CBMAB-C3462-CN)

Rabbit Anti-FCER2 Recombinant Antibody (E28-S) (CAT#: CBMAB-C4917WJ)

Mouse Anti-FCER2 Recombinant Antibody (MHM6) (CAT#: CBMAB-C11574-LY)

Mouse Anti-FCER2 Recombinant Antibody (CBXC-2651) (CAT#: CBMAB-C4067-CQ)

Mouse Anti-FCER2 (Extracellular domain) Recombinant Antibody (CBXF-0443) (CAT#: CBMAB-F2260-CQ)

Mouse Anti-FCER2 Recombinant Antibody (D3.6) (CAT#: CBMAB-C2875WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry