Mouse Anti-FKBP11 Recombinant Antibody (CBYC-P067) (CBMAB-P0339-YC)

Provided herein is a Mouse monoclonal antibody against Human FK506 Binding Protein 11. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all FKBP11 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYC-P067

Antibody Isotype

IgG2a

Application

ELISA, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

FK506 Binding Protein 11

Introduction

FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin.

Entrez Gene ID

51303

UniProt ID

Q9NYL4

Alternative Names

FKBP19

Function

PPIases accelerate the folding of proteins during protein synthesis.

Biological Process

Chaperone-mediated protein folding Source: InterPro

Cellular Location

Membrane

Topology

Helical: 156-176

References

Herrema, H., Guan, D., Choi, J. W., Feng, X., Hernandez, M. A. S., Faruk, F., ... & Ozcan, U. (2022). FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity. Cell Metabolism, 34(7), 1004-1022.

Qiu, L., Liu, H., Wang, S., Dai, X. H., Shang, J. W., Lian, X. L., ... & Zhang, J. (2021). FKBP11 promotes cell proliferation and tumorigenesis via p53-related pathways in oral squamous cell carcinoma. Biochemical and Biophysical Research Communications, 559, 183-190.

Wang, X., Cui, X., Zhu, C., Li, M., Zhao, J., Shen, Z., ... & Zhou, G. (2018). FKBP11 protects intestinal epithelial cells against inflammation‑induced apoptosis via the JNK‑caspase pathway in Crohn's disease. Molecular Medicine Reports, 18(5), 4428-4438.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-FKBP11 Recombinant Antibody (CBXF-1751)

Mouse Anti-FKBP11 (AA 28-201) Recombinant Antibody (CBXF-0702)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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