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Mouse Anti-FKBP2 Recombinant Antibody (33B) (CBMAB-AP2294LY)

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
33B
Antibody Isotype
IgG1
Application
ELISA, IHC, WB

Basic Information

Immunogen
Fusion protein of FKBP2
Specificity
Human, Rat
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
FK506 Binding Protein 2
Introduction
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Entrez Gene ID
Human2286
Rat293702
UniProt ID
HumanP26885
RatD3ZZR9
Alternative Names
FK506 Binding Protein 2; FK506 Binding Protein 2, 13kDa; 13 KDa FK506-Binding Protein; Rapamycin-Binding Protein; Immunophilin FKBP13; Proline Isomerase; PPIase FKBP2; 13 KDa FKBP; Rotamase; FKBP-13;
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Biological Process
Chaperone-mediated protein folding Source: InterPro
Cellular Location
Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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