Mouse Anti-GNL2 Recombinant Antibody (CBLG1-3199) (CBMAB-G4164-LY)

This product is antibody recognizes GNL2. The antibody CBLG1-3199 immunoassay techniques such as: WB.
See all GNL2 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Mouse, Rat, Human

Clone

CBLG1-3199

Antibody Isotype

IgG

Application

Basic Information

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

guanine nucleotide binding protein-like 2 (nucleolar)

Entrez Gene ID

Human	29889
Mouse	230737
Rat	362593

UniProt ID

Human	Q13823
Mouse	Q99LH1
Rat	Q4KLJ3

Function

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity).

May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195).

Biological Process

Ribosome biogenesis Source: UniProtKB-KW

Cellular Location

Nucleolus

References

Wang, Z., Chen, H., Peng, L., He, Y., Wei, J., & Zhang, X. (2023). DNER and GNL2 are differentially m6A methylated in periodontitis in comparison with periodontal health revealed by m6A microarray of human gingival tissue and transcriptomic analysis. Journal of Periodontal Research.

Nakamura, K., Reid, B. M., Chen, A., Chen, Z., Goode, E. L., Permuth, J. B., ... & Karreth, F. A. (2022). Functional analysis of the 1p34. 3 risk locus implicates GNL2 in high-grade serous ovarian cancer. The American Journal of Human Genetics, 109(1), 116-135.

Dong, Y., Cai, Q., Fu, L., Liu, H., Ma, M., & Wu, X. (2021). Study of the G Protein Nucleolar 2 Value in Liver Hepatocellular Carcinoma Treatment and Prognosis. BioMed Research International, 2021.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-GNL2 Recombinant Antibody (CBLG1-3200)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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