Mouse Anti-GNL2 Recombinant Antibody (CBLG1-3200) (CBMAB-G4165-LY)

Name: Mouse Anti-GNL2 Recombinant Antibody (CBLG1-3200)
SKU: CBMAB-G4165-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBLG1-3200

Application

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

guanine nucleotide binding protein-like 2 (nucleolar)

Entrez Gene ID

29889

UniProt ID

Q13823

Alternative Names

HUMAUANTIG; NGP1; Ngp-1; Nog2; Nug2

Function

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity).

May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195).

Biological Process

Ribosome biogenesis Source: UniProtKB-KW

Cellular Location

Nucleolus

Wang, Z., Chen, H., Peng, L., He, Y., Wei, J., & Zhang, X. (2023). DNER and GNL2 are differentially m6A methylated in periodontitis in comparison with periodontal health revealed by m6A microarray of human gingival tissue and transcriptomic analysis. Journal of Periodontal Research.

Nakamura, K., Reid, B. M., Chen, A., Chen, Z., Goode, E. L., Permuth, J. B., ... & Karreth, F. A. (2022). Functional analysis of the 1p34. 3 risk locus implicates GNL2 in high-grade serous ovarian cancer. The American Journal of Human Genetics, 109(1), 116-135.

Dong, Y., Cai, Q., Fu, L., Liu, H., Ma, M., & Wu, X. (2021). Study of the G Protein Nucleolar 2 Value in Liver Hepatocellular Carcinoma Treatment and Prognosis. BioMed Research International, 2021.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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