Sign in or Register   Sign in or Register
  |  

Mouse Anti-GPR1 Recombinant Antibody (K1G4) (CBMAB-G4629-LY)

This product is antibody recognizes GPR1. The antibody K1G4 immunoassay techniques such as: IHC-P.
See all GPR1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
K1G4
Antibody Isotype
IgG2a
Application
IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G protein-coupled receptor 1
Entrez Gene ID
2825
UniProt ID
P46091
Function
Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis (PubMed:18165312, PubMed:27716822).

Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too (PubMed:27716822).

Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway (By similarity).

(Microbial infection) Coreceptor for HIV-1.
Biological Process
Glucose homeostasis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: ProtInc
Neuropeptide signaling pathway Source: GO_Central
Cellular Location
Cell membrane. Internalizes in presence of its ligand, TAFA1 (By similarity). Internalizes efficiently in response to RARRES2 (PubMed:27716822).
Topology
Extracellular: 1-41
Helical: 42-62
Cytoplasmic: 63-73
Helical: 74-94
Extracellular: 95-112
Helical: 113-133
Cytoplasmic: 134-154
Helical: 155-175
Extracellular: 176-210
Helical: 211-231
Cytoplasmic: 232-247
Helical: 248-268
Extracellular: 269-286
Helical: 287-307
Cytoplasmic: 308-355
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GPR1 Recombinant Antibody (K1G4)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare