Rabbit Anti-GPR150 Recombinant Antibody (EG1382) (CBMAB-EN1661-LY)

Name: Rabbit Anti-GPR150 Recombinant Antibody (EG1382)
SKU: CBMAB-EN1661-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1382

Application

WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human GPR150.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

G Protein-Coupled Receptor 150

Introduction

This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]

Entrez Gene ID

285601

UniProt ID

Q8NGU9

Alternative Names

G Protein-Coupled Receptor 150; Probable G-Protein Coupled Receptor 150; Seven Transmembrane Helix Receptor; PGR11;

Function

Orphan receptor.

Biological Process

G protein-coupled receptor signaling pathway Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-3
Helical: 4-24
Cytoplasmic: 25-43
Helical: 44-64
Extracellular: 65-81
Helical: 82-102
Cytoplasmic: 103-162
Helical: 163-183
Extracellular: 184-237
Helical: 238-258
Cytoplasmic: 259-293
Helical: 294-314
Extracellular: 315-334
Helical: 335-355
Cytoplasmic: 356-434

Rump, M. T., Kozma, M. T., Pawar, S. D., & Derby, C. D. (2021). G protein-coupled receptors as candidates for modulation and activation of the chemical senses in decapod crustaceans. Plos one, 16(6), e0252066.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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