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Rabbit Anti-GPR150 Recombinant Antibody (EG1382) (CBMAB-EN1661-LY)

The product is antibody recognizes GPR150. The antibody EG1382 immunoassay techniques such as: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000.
See all GPR150 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1382
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GPR150.
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G Protein-Coupled Receptor 150
Introduction
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]
Entrez Gene ID
285601
UniProt ID
Q8NGU9
Alternative Names
G Protein-Coupled Receptor 150; Probable G-Protein Coupled Receptor 150; Seven Transmembrane Helix Receptor; PGR11;
Function
Orphan receptor.
Biological Process
G protein-coupled receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-3
Helical: 4-24
Cytoplasmic: 25-43
Helical: 44-64
Extracellular: 65-81
Helical: 82-102
Cytoplasmic: 103-162
Helical: 163-183
Extracellular: 184-237
Helical: 238-258
Cytoplasmic: 259-293
Helical: 294-314
Extracellular: 315-334
Helical: 335-355
Cytoplasmic: 356-434
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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