Mouse Anti-GPR22 Recombinant Antibody (CBFYH-0455) (CBMAB-H0498-FY)

Name: Mouse Anti-GPR22 Recombinant Antibody (CBFYH-0455)
SKU: CBMAB-H0498-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0455

Application

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

G protein-coupled receptor 22

Introduction

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein.

Entrez Gene ID

2845

UniProt ID

Q99680

Alternative Names

G Protein-Coupled Receptor 22

Function

Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (PubMed:18539757).

May be involved in ciliogenesis (By similarity).

Biological Process

Cell projection organization Source: UniProtKB-KW
G protein-coupled receptor signaling pathway Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-45
Helical: 46-66
Cytoplasmic: 67-85
Helical: 86-106
Extracellular: 107-115
Helical: 116-136
Cytoplasmic: 137-156
Helical: 157-177
Extracellular: 178-208
Helical: 209-229
Cytoplasmic: 230-315
Helical: 316-336
Extracellular: 337-349
Helical: 350-370
Cytoplasmic: 371-433

Watkins, L. R., & Orlandi, C. (2021). In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activity. British Journal of Pharmacology, 178(15), 2963-2975.

Atanes, P., Ashik, T., & Persaud, S. J. (2021). Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for metabolic regulation. Pharmacology & Therapeutics, 228, 107928.

Guns, L. A., Lories, R., & Cailotto, F. (2018). G-proteïne-gekoppelde-receptor 22 (GPR22): een nieuw doelwit in osteoartrose?.

Egerod, K. L., Petersen, N., Timshel, P. N., Rekling, J. C., Wang, Y., Liu, Q., ... & Gautron, L. (2018). Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms. Molecular metabolism, 12, 62-75.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Rabbit Anti-GPR22 Recombinant Antibody (EG1397) (CAT#: CBMAB-EN1676-LY)

Isotype control

For research use only. Not intended for any clinical use.

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