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Mouse Anti-GPT Recombinant Antibody (CBLG1-213) (CBMAB-G0739-LY)

This product is antibody recognizes GPT. The antibody CBLG1-213 immunoassay techniques such as: IHC, WB.
See all GPT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-213
Antibody Isotype
IgG
Application
IHC, WB

Basic Information

Immunogen
Alanine Aminotransferase
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% NaN3
Concentration
0.5 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glutamic--Pyruvic Transaminase
Introduction
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
Entrez Gene ID
2875
UniProt ID
P24298
Alternative Names
Glutamic--Pyruvic Transaminase; Glutamic-Pyruvate Transaminase (Alanine Aminotransferase); Glutamate Pyruvate Transaminase 1; Glutamic--Pyruvic Transaminase 1; Alanine Aminotransferase; EC 2.6.1.2; GPT 1;
Function
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).
Biological Process
Biosynthetic process Source: InterPro
Cellular response to insulin stimulus Source: Ensembl
L-alanine catabolic process Source: UniProtKB-UniPathway
Positive regulation of gluconeogenesis Source: Ensembl
Response to starvation Source: Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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