GPT

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
Full Name
Glutamic--Pyruvic Transaminase
Function
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity).
Biological Process
Biosynthetic process Source: InterPro
Cellular response to insulin stimulus Source: Ensembl
L-alanine catabolic process Source: UniProtKB-UniPathway
Positive regulation of gluconeogenesis Source: Ensembl
Response to starvation Source: Ensembl
Cellular Location
Cytoplasm
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Anti-GPT antibodies

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Mouse Anti-GPT Recombinant Antibody (CAP850) (CBMAB-AP2595LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP850
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (8) (CBMAB-AP2594LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: 8
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBYC-A971) (CBMAB-A4444-YC)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYC-A971
Application*: IC, C, P, E, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBYC-A970) (CBMAB-A4443-YC)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYC-A970
Application*: E, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (15j4) (CBMAB-A4438-YC)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: 15j4
Application*: E, IC, IH, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (M1) (CBMAB-G4711-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cat
Clone: M1
Application*: E
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBLG1-1665) (CBMAB-G4714-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBLG1-1665
Application*: WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBLG1-1664) (CBMAB-G4713-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-1664
Application*: E, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBLG1-1663) (CBMAB-G4712-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBLG1-1663
Application*: E, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (4E2) (CBMAB-G4710-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4E2
Application*: E, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (11) (CBMAB-G4708-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 11
Application*: WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBLG1-213) (CBMAB-G0739-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-213
Application*: IH, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBLG1-212) (CBMAB-G0738-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBLG1-212
Application*: E, WB
Datasheet SDS

Mouse Anti-GPT Recombinant Antibody (CBLG1-211) (CBMAB-G0737-LY)

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Target: GPT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-211
Application*: E, IC, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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