Sign in or Register   Sign in or Register
  |  

Mouse Anti-GSTT1 Recombinant Antibody (CBLG1-2069) (CBMAB-G5594-LY)

This product is antibody recognizes GSTT1. The antibody CBLG1-2069 immunoassay techniques such as: ELISA, IHC, IP, WB.
See all GSTT1 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Human
Clone
CBLG1-2069
Antibody Isotype
IgG
Application
ELISA, IHC, IP, WB

Basic Information

Immunogen
This Protein A purified antibody was prepared by repeated immunizations in mice with T1 Protein
Specificity
Mouse, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
glutathione S-transferase theta 1
Introduction
The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Entrez Gene ID
Human2952
Mouse14871
UniProt ID
HumanP30711
MouseQ64471
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.
Biological Process
Glutathione metabolic process Source: UniProtKB
Cellular Location
Cytoplasm

Nakanishi, G., Bertagnolli, L. S., Pita-Oliveira, M., Scudeler, M. M., Torres-Loureiro, S., Almeida-Dantas, T., ... & Rodrigues-Soares, F. (2022). GSTM1 and GSTT1 polymorphisms in healthy volunteers–a worldwide systematic review. Drug Metabolism Reviews, 54(1), 37-45.

Abbas, M., Verma, S., Verma, S., Siddiqui, S., Khan, F. H., Raza, S. T., ... & Mahdi, F. (2021). Association of GSTM1 and GSTT1 gene polymorphisms with COVID‐19 susceptibility and its outcome. Journal of medical virology, 93(9), 5446-5451.

Saadat, M. (2020). An evidence for correlation between the glutathione S-transferase T1 (GSTT1) polymorphism and outcome of COVID-19. Clinica chimica acta; international journal of clinical chemistry, 508, 213.

Chanhom, N., Udomsinprasert, W., Mahasirimongkol, S., Wattanapokayakit, S., & Jittikoon, J. (2020). GSTM1 and GSTT1 genetic polymorphisms and their association with antituberculosis drug‑induced liver injury. Biomedical Reports, 12(4), 153-162.

Song, L., Yang, C., & He, X. F. (2020). Individual and combined effects of GSTM1 and GSTT1 polymorphisms on colorectal cancer risk: an updated meta-analysis. Bioscience Reports, 40(8).

Li, S., Xue, F., Zheng, Y., Yang, P., Lin, S., Deng, Y., ... & Chen, S. (2019). GSTM1 and GSTT1 null genotype increase the risk of hepatocellular carcinoma: evidence based on 46 studies. Cancer cell international, 19(1), 1-12.

Klusek, J., Nasierowska-Guttmejer, A., Kowalik, A., Wawrzycka, I., Lewitowicz, P., Chrapek, M., & Głuszek, S. (2018). GSTM1, GSTT1, and GSTP1 polymorphisms and colorectal cancer risk in Polish nonsmokers. Oncotarget, 9(30), 21224.

Benabdelkrim, M., Djeffal, O., & Berredjem, H. (2018). GSTM1 and GSTT1 polymorphisms and susceptibility to prostate cancer: a case-control study of the Algerian population. Asian Pacific journal of cancer prevention: APJCP, 19(10), 2853.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GSTT1 Recombinant Antibody (CBLG1-2069)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare