Sign in or Register   Sign in or Register
  |  

Mouse Anti-GTF2E2 Recombinant Antibody (8C160) (CBMAB-G5685-LY)

This product is antibody recognizes GTF2E2. The antibody 8C160 immunoassay techniques such as: WB.
See all GTF2E2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
8C160
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Partial sequence of recombinant full-length protein to human General Transcription Factor IIE, Polypeptide 2beta, 34kD
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
1% BSA
Concentration
0.1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
General Transcription Factor IIE Subunit 2
Entrez Gene ID
Human2961
Mouse68153
Rat306516
UniProt ID
HumanP29084
MouseQ9D902
RatD3ZCP9
Alternative Names
General Transcription Factor IIE Subunit 2; General Transcription Factor IIE; Polypeptide 2; Beta 34kDa; TFIIE Beta Subunit; TFIIE-Beta; TF2E2; General Transcription Factor IIE; Polypeptide 2 (Beta Subunit; 34kD);
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Biological Process
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: GO_Central
Cellular Location
Nucleus
Involvement in disease
Trichothiodystrophy 6, non-photosensitive (TTD6):
A form of trichothiodystrophy, a disease characterized by sulfur-deficient brittle hair and multisystem variable abnormalities. The spectrum of clinical features varies from mild disease with only hair involvement to severe disease with cutaneous, neurologic and profound developmental defects. Ichthyosis, intellectual and developmental disabilities, decreased fertility, abnormal characteristics at birth, ocular abnormalities, short stature, and infections are common manifestations. There are both photosensitive and non-photosensitive forms of the disorder. TTD6 patients do not manifest cutaneous photosensitivity. Inheritance pattern has been reported to be autosomal recessive.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GTF2E2 Recombinant Antibody (8C160)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare