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Mouse Anti-H2AX (Phosphorylated S139) Recombinant Antibody (2A9-B5) (PTM-CBMAB-0334LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
2A9-B5
Antibody Isotype
IgG2a
Application
WB, IF

Basic Information

Immunogen
The immunogen for H2AX(Pi-Ser139) antibody: Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
H2AX
Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
Entrez Gene ID
Human3014
Mouse15270
UniProt ID
HumanP16104
MouseP27661
Alternative Names
H2A Histone Family Member X; Histone H2A.X; H2A/X; H2AX; H2A Histone Family, Member X; H2AX Histone; Histone H2AX; H2A.X;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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