Rabbit Anti-HDAC8 (Phospho-Ser39) Recombinant Antibody (EG1500) (CBMAB-EN1794-LY)

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Basic Information

Host Animal
Rabbit
Clone
EG1500
Application
IHC: 1:50~1:100
Immunogen
The antibody was produced against synthesized phosphopeptide derived from human HDAC8 around the phosphorylation site of serine 39 (R-A-SP-M-V).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
histone deacetylase 8
Introduction
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
Human55869
Mouse70315
Rat363481
UniProt ID
HumanQ9BY41
MouseQ8VH37
RatB1WC68
Alternative Names
HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1
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For research use only. Not intended for any clinical use.

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