Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0205) (CBMAB-V208-0230-FY)

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Basic Information

Host Animal
Mouse
Clone
CBMW-H0205
Application
ELISA, WB
Specificity
HIV
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 40% glycerol
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Human Immunodeficiency Virus-1 Gag Polyprotein
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).
UniProt ID
Alternative Names
gag, HIV-1 Gag Polyprotein
Function
Mediates, with Gag-Pol polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).
Biological Process
Viral budding via host ESCRT complex Source: UniProtKB
Cellular Location
Host cell membrane; Host multivesicular body. These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly.
PTM
Gag-Pol polyprotein: Specific enzymatic cleavages by the viral protease yield mature proteins.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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