HIV-1 Gag

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).
Full Name
Human Immunodeficiency Virus-1 Gag Polyprotein
Function
Mediates, with Gag-Pol polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).
Biological Process
Viral budding via host ESCRT complex Source: UniProtKB
Cellular Location
Host cell membrane; Host multivesicular body. These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly.
PTM
Gag-Pol polyprotein: Specific enzymatic cleavages by the viral protease yield mature proteins.
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Anti-HIV-1 Gag antibodies

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Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0753) (CBMAB-V208-0855-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG1
Specificity: HIV
Clone: CBMW-H0753
Application*: IF, IP, WB
Datasheet SDS

Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0752) (CBMAB-V208-0854-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG1
Specificity: HIV
Clone: CBMW-H0752
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0751) (CBMAB-V208-0852-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgA, κ
Specificity: HIV
Clone: CBMW-H0751
Application*: E, WB
Datasheet SDS

Mouse Anti-HIV-1 Gag (AA 1-133) Recombinant Antibody (CBMW-H0284) (CBMAB-V208-0322-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG2b
Specificity: HIV
Clone: CBMW-H0284
Application*: E, WB
Datasheet SDS

Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0205) (CBMAB-V208-0230-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: HIV
Clone: CBMW-H0205
Application*: E, WB
Datasheet SDS

Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0204) (CBMAB-V208-0229-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG1
Specificity: HIV
Clone: CBMW-H0204
Application*: IP
Datasheet SDS

Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0146) (CBMAB-V208-0170-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG1
Specificity: HIV
Clone: CBMW-H0146
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-HIV-1 Gag Recombinant Antibody (CBMW-H0144) (CBMAB-V208-0168-FY)

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Target: HIV-1 Gag
Host: Mouse
Antibody Isotype: IgG
Specificity: HIV
Clone: CBMW-H0144
Application*: E, IC, IH, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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