Mouse Anti-IFNE1 Recombinant Antibody (3B8) (CBMAB-A4284-LY)

Name: Mouse Anti-IFNE1 Recombinant Antibody (3B8)
SKU: CBMAB-A4284-LY
Rating: 5 (1 reviews)

See all IFNE1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3B8

Application

WB, ELISA

Immunogen

IFNE1 (NP_795372, 109 a.a. ~ 208 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

interferon, epsilon

Entrez Gene ID

3458

UniProt ID

P01579

Alternative Names

IFN-E; IFNE1; IFNT1; MGC119018; MGC119020; PRO655

Function

Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections (By similarity).

Biological Process

Adaptive immune response Source: GO_Central
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to bacterium Source: UniProtKB
Defense response to virus Source: UniProtKB
Humoral immune response Source: GO_Central
Natural killer cell activation involved in immune response Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central

Cellular Location

Secreted

Taylor, B. D., Criscitiello, M. F., Bazer, F. W., Richardson, L. S., Noah, A., & Haggerty, C. L. (2023). Functional interferon‐epsilon gene polymorphisms and sexually transmitted infections of the endometrium. American Journal of Reproductive Immunology, 90(2), e13754.

Ahmad, H. I., Jameel, L., Zahra, Q., Zhou, J., Li, L., Zhang, X., ... & Chen, J. (2023). Molecular Evolution of Interferon-Epsilon (IFNε) Pseudogene Modulates Innate and Specific Antiviral Immunity in Manis javanica. Journal of Zoological Systematics and Evolutionary Research, 2023.

Gu, Z., Liu, J., Qin, L., Zhang, Y., Cui, W., Huang, H., ... & Zhang, H. (2023). WTAP-mediated m6A modification of IFNE is required for antiviral defense in condyloma acuminata. Journal of Dermatological Science.

Miller, D., Romero, R., Kacerovsky, M., Musilova, I., Galaz, J., Garcia-Flores, V., ... & Gomez-Lopez, N. (2022). Defining a role for Interferon Epsilon in normal and complicated pregnancies. Heliyon, 8(7), e09952.

Barriga, F. M., Tsanov, K. M., Ho, Y. J., Sohail, N., Zhang, A., Baslan, T., ... & Lowe, S. W. (2022). MACHETE identifies interferon-encompassing chromosome 9p21. 3 deletions as mediators of immune evasion and metastasis. Nature Cancer, 3(11), 1367-1385.

Taylor, B. D., Criscitiello, M. F., Hernandez, T., Norwood, B., Noah, A. I., & Bazer, F. W. (2022). Interferon epsilon and preterm birth subtypes; a new piece of the type I interferon puzzle during pregnancy?. American Journal of Reproductive Immunology, 87(4), e13526.

Marks, Z. R., Campbell, N., deWeerd, N. A., Lim, S. S., Gearing, L. J., Bourke, N. M., & Hertzog, P. J. (2019, June). Properties and functions of the novel type I interferon epsilon. In Seminars in Immunology (Vol. 43, p. 101328). Academic Press.

Nickodem, C., Criscitiello, M. F., Bazer, F., Abiodun‐Ojo, O., & Taylor, B. D. (2018). Interferon epsilon in the reproductive tract of healthy and genital herpes simplex virus‐infected pregnant women: Results of a pilot study. American Journal of Reproductive Immunology, 80(3), e12995.

Fischer, C. D., Wachoski-Dark, G. L., Grant, D. M., Bramer, S. A., & Klein, C. (2018). Interferon epsilon is constitutively expressed in equine endometrium and up-regulated during the luteal phase. Animal reproduction science, 195, 38-43.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-IFNE1 Recombinant Antibody (3B8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry