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Mouse Anti-ITGAE Recombinant Antibody (OX62) (CBMAB-O0082-CQ)

This product is a mouse antibody that recognizes ITGAE. The antibody OX62 can be used for immunoassay techniques such as: FC, IHC-Fr, IP.
See all ITGAE antibodies
Published Data
Fig.1 Flt3L-Dependent CD103+ CD11b− DCs Not Monocyte-Derived DCs are Required for Flagellin-Mediated IL-23 Expression.
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Fig.2 CD103+ CD11b+ DCs but not CD103− CD11b+ DCs Express IL-23p19 and IL-12p40 in Response to TLR5 Stimulation.
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Summary

Host Animal
Mouse
Specificity
Rat
Clone
OX62
Antibody Isotype
IgG1
Application
FC, IHC-Fr, IP

Basic Information

Immunogen
Density gradient enriched PVG rat thoracic duct dendritic cells
Specificity
Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Integrin Subunit Alpha E
Introduction
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains.
Entrez Gene ID
83577
UniProt ID
M0R6T8
Alternative Names
Integrin alpha E1, epithelial-associated; integrin alpha-E; integrin, alpha E, epithelial-associated
Function
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Biological Process
Cell adhesionIEA:UniProtKB-KW
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Cellular Location
Membrane
Topology
Extracellular: 19-1124
Helical: 1125-1147
Cytoplasmic: 1148-1179
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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