ITGAE

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
Full Name
Integrin Subunit Alpha E
Function
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Biological Process
Cell adhesionIEA:UniProtKB-KW
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Cellular Location
Membrane
Topology
Extracellular: 19-1124
Helical: 1125-1147
Cytoplasmic: 1148-1179
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Anti-ITGAE antibodies

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Rat Anti-ITGAE Recombinant Antibody (A676) (CBMAB-AP11926LY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: A676
Application*: FC, IHC, IP
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (B-ly7) (CBMAB-C3678-CN)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-ly7
Application*: FC
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (3H1798) (CBMAB-C3677-CN)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Monkey
Clone: 3H1798
Application*: FC, IH, IP
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (CBWJC-2227) (CBMAB-C3035WJ)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-2227
Application*: B, IF, F
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (CBWJC-2226) (CBMAB-C3033WJ)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2226
Application*: IF, IP, F
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (CBWJC-2225) (CBMAB-C3032WJ)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2225
Application*: F, C
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (CBYY-C0149) (CBMAB-C0496-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0149
Application*: F, IH, IP
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (CBFYC-2809) (CBMAB-C2885-FY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2809
Application*: F, IP
Datasheet SDS

Hamster Anti-ITGAE Recombinant Antibody (CBFYC-2808) (CBMAB-C2884-FY)

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Target: ITGAE
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2808
Application*: F, IH
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (7A3) (CBMAB-C8554-LY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 7A3
Application*: P, F
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (2G5.1) (CBMAB-C5197-LY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2G5.1
Application*: F, C, IP
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (14L142) (CBMAB-C3091-LY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L142
Application*: F, IH
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (14L141) (CBMAB-C3090-LY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L141
Application*: F, IP
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (3H1797) (CBMAB-C1205-LY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1797
Application*: F, IH, IP
Datasheet SDS

Hamster Anti-ITGAE Recombinant Antibody (2E7) (CBMAB-C0880-LY)

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Target: ITGAE
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: 2E7
Application*: C, FN, P, F
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (OX62) (CBMAB-O0082-CQ)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX62
Application*: F, C, IP
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (CBYY-I1231) (CBMAB-I2400-YY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I1231
Application*: F, IH
Datasheet SDS

Mouse Anti-ITGAE (AA 82-113) Recombinant Antibody (Ber-ACT8) (CBMAB-I1998-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Ber-ACT8
Application*: WB, F, IH, IP, C, MC
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (AX.14) (CBMAB-I1932-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AX.14
Application*: F
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (AP-MAB0828) (CBMAB-I1903-YY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: AP-MAB0828
Application*: IP, C, F, I, MC
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (6B8) (CBMAB-I1552-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 6B8
Application*: E, WB
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (BP6) (CBMAB-I1164-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: BP6
Application*: IH, IP, IF
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (CBYY-I0501) (CBMAB-I1156-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0501
Application*: F, IH, C
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (CBYY-I0446) (CBMAB-I1046-YY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I0446
Application*: F, IH, P, MC
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (OX-62) (CBMAB-I0970-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX-62
Application*: F, IH, C, IP, WB
Datasheet SDS

Mouse Anti-ITGAE Recombinant Antibody (LF61) (CBMAB-I0801-YY)

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Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LF61
Application*: F, C, IP
Datasheet SDS

Rat Anti-ITGAE Recombinant Antibody (CBYY-I0266) (CBMAB-I0743-YY)

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-I0266
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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