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ITGAE

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
Full Name
Integrin Subunit Alpha E
Function
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Biological Process
Cell adhesionIEA:UniProtKB-KW
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Cellular Location
Membrane
Topology
Extracellular: 19-1124
Helical: 1125-1147
Cytoplasmic: 1148-1179

Anti-ITGAE antibodies

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Target: ITGAE
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: A676
Application*: FC, IHC, IP
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-ly7
Application*: FC
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Monkey
Clone: 3H1798
Application*: FC, IH, IP
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-2227
Application*: B, IF, F
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2226
Application*: IF, IP, F
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2225
Application*: F, C
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0149
Application*: F, IH, IP
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2809
Application*: F, IP
Target: ITGAE
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2808
Application*: F, IH
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 7A3
Application*: P, F
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2G5.1
Application*: F, C, IP
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L142
Application*: F, IH
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L141
Application*: F, IP
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1797
Application*: F, IH, IP
Target: ITGAE
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: 2E7
Application*: C, FN, P, F
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX62
Application*: F, C, IP
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I1231
Application*: F, IH
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Ber-ACT8
Application*: WB, F, IH, IP, C, MC
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AX.14
Application*: F
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: AP-MAB0828
Application*: IP, C, F, I, MC
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 6B8
Application*: E, WB
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: BP6
Application*: IH, IP, IF
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0501
Application*: F, IH, C
Target: ITGAE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I0446
Application*: F, IH, P, MC
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX-62
Application*: F, IH, C, IP, WB
Target: ITGAE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LF61
Application*: F, C, IP
Target: ITGAE
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-I0266
Application*: WB
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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