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Mouse Anti-LCN1 Recombinant Antibody (10B10) (CBMAB-L0826-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Lipocalin 1 (LCN1). The antibody can be used for immunoassay techniques, such as WB, IF.
See all LCN1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
10B10
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Immunogen
Purified recombinant fragment of LCN1 expressed in E. coli.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Preservative
0.03% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Lipocalin 1
Introduction
lipocalin 1 (LCN1) is a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. LCN1 is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. LCN1 may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9.
Entrez Gene ID
UniProt ID
Alternative Names
Lipocalin 1; Von Ebner Gland Protein; Tear Prealbumin; Tear Lipocalin; VEG Protein; VEGP; TP; Lipocalin 1 (Protein Migrating Faster Than Albumin, Tear Prealbumin);Protein Migrating Faster Than Albumin; Lipocalin 1 (Tear Prealbumin); Lipocalin 1-Like 2; Lipocalin-1; PMFA; TLC; Tlc
Function
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
Biological Process
ProteolysisManual Assertion Based On ExperimentTAS:ProtInc
Response to stimulusIEA:UniProtKB-KW
Retina homeostasisManual Assertion Based On ExperimentHEP:UniProtKB
Sensory perception of tasteIEA:UniProtKB-KW
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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