Mouse Anti-PGM1 Recombinant Antibody (84G2) (CBMAB-P1593-YC)

Name: Mouse Anti-PGM1 Recombinant Antibody (84G2)
SKU: CBMAB-P1593-YC
Rating: 5 (1 reviews)

See all PGM1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

84G2

Application

WB, ELISA, ICC, IF

Immunogen

Recombinant human PGM1 (1-562aa) purified from E. coli

Specificity

Human, Mouse

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Phosphoglucomutase 1

Introduction

PGM1 is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.

Entrez Gene ID

Human	5236
Mouse	72157

UniProt ID

Human	P36871
Mouse	Q9D0F9

Alternative Names

Phosphoglucomutase 1; Glucose Phosphomutase 1; EC 5.4.2.2; PGM 1; Phosphoglucomutase-1; EC 5.4.2; CDG1T; GSD14;

Function

This enzyme participates in both the breakdown and synthesis of glucose.

Biological Process

Carbohydrate metabolic processManual Assertion Based On ExperimentIBA:GO_Central
GluconeogenesisManual Assertion Based On ExperimentTAS:UniProtKB
Glucose metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Glycolytic processManual Assertion Based On ExperimentTAS:UniProtKB

Cellular Location

Cytoplasm

Involvement in disease

Congenital disorder of glycosylation 1T (CDG1T):
A form of congenital disorder of glycosylation, a multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.

PTM

Phosphorylation at Thr-467 by PAK1 significantly enhances enzymatic activity.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-PGM1 Recombinant Antibody (84G2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-PGM1 Recombinant Antibody (CBYC-P331) (CAT#: CBMAB-P1594-YC)

Mouse Anti-PGM1 Recombinant Antibody (3B8-H4) (CAT#: CBMAB-P1592-YC)

Mouse Anti-PGM1 Recombinant Antibody (CF336) (CAT#: CBMAB-FT165LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry