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Mouse Anti-POLR2C Recombinant Antibody (2F9) (CBMAB-R0642-CN)

This product is a Mouse antibody that recognizes POLR2C. The antibody 2F9 can be used for immunoassay techniques such as: ELISA, WB, ICC, IP.
See all POLR2C antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F9
Antibody Isotype
IgG3, κ
Application
ELISA, WB, ICC, IP

Basic Information

Specificity
Human
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid

Target

Full Name
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Introduction
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]
Entrez Gene ID
5432
UniProt ID
P19387
Alternative Names
RPB3; RPB31; hRPB33; hsRPB3
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).
Biological Process
Transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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