Sign in or Register   Sign in or Register
  |  

Mouse Anti-PRAP1 Recombinant Antibody (2B4) (CBMAB-A6993-LY)

The product is antibody recognizes PRAP1. The antibody 2B4 immunoassay techniques such as: WB, ELISA.
See all PRAP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2B4
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PRAP1 (NP_660203.2, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
proline-rich acidic protein 1
Entrez Gene ID
118471
UniProt ID
Q96NZ9
Alternative Names
MGC126792; PRO1195; RP11-122K13.6; UPA
Function
Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion (By similarity).
Protects the gastrointestinal epithelium from irradiation-induced apoptosis (By similarity).
May play an important role in maintaining normal growth homeostasis in epithelial cells (PubMed:14583459).
Involved in p53/TP53-dependent cell survival after DNA damage (PubMed:23235459).
May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas (PubMed:24374861).
Biological Process
Cellular response to DNA damage stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Cellular response to X-rayISS:UniProtKB
Deactivation of mitotic spindle assembly checkpointManual Assertion Based On ExperimentIDA:UniProtKB
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of intestinal lipid absorptionISS:UniProtKB
Positive regulation of phospholipid transportISS:UniProtKB
Positive regulation of triglyceride transportISS:UniProtKB
Cellular Location
Secreted
Endoplasmic reticulum
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PRAP1 Recombinant Antibody (2B4)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare