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Mouse Anti-PRELP Recombinant Antibody (3H1) (CBMAB-P2755-YC)

Provided herein is a Mouse monoclonal antibody against Human Proline And Arginine Rich End Leucine Rich Repeat Protein. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PRELP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3H1
Antibody Isotype
IgM, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa281-365 from human PRELP with GST tag.
Specificity
Human
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Proline And Arginine Rich End Leucine Rich Repeat Protein
Introduction
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Entrez Gene ID
5549
UniProt ID
P51888
Alternative Names
MST161; MSTP161; SLRR2A
Function
May anchor basement membranes to the underlying connective tissue.
Biological Process
Cellular senescenceIEA:Ensembl
Skeletal system developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted, extracellular space, extracellular matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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