Rabbit Anti-SESTD1 Recombinant Antibody (CBXS-1367) (CBMAB-S4225-CQ)

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Basic Information

Host Animal
Rabbit
Clone
CBXS-1367
Application
WB, IF
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
SEC14 And Spectrin Domain Containing 1
Introduction
SESTD1 (SEC14 And Spectrin Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include phosphatidylinositol-4,5-bisphosphate binding and phosphatidylserine binding.
Entrez Gene ID
Human91404
Mouse228071
Rat295678
UniProt ID
HumanQ86VW0
MouseQ80UK0
RatB5DFL9
Alternative Names
SEC14 And Spectrin Domain Containing 1; Huntingtin-Interacting Protein-Like Protein; SEC14 And Spectrin Domains 1; Protein SOLO; SOLO; SEC14 Domain And Spectrin Repeat-Containing Protein 1;
Function
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
Biological Process
Negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
Cellular Location
Intermediate filament cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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