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Mouse Anti-SF3A1 Recombinant Antibody (CBXS-3879) (CBMAB-S1148-CQ)

This product is a mouse antibody that recognizes SF3A1. The antibody CBXS-3879 can be used for immunoassay techniques such as: WB.
See all SF3A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3879
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Splicing Factor 3a Subunit 1
Introduction
This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing.
Entrez Gene ID
10291
UniProt ID
Q15459
Alternative Names
Splicing Factor 3a Subunit 1; Splicing Factor 3a, Subunit 1, 120kDa; Splicing Factor 3a, Subunit 1, 120kD; Spliceosome-Associated Protein 114; SAP 114; SF3A120; SAP114;
Function
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex (PubMed:10882114, PubMed:11533230).
Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes (PubMed:29360106, PubMed:30315277).
Biological Process
Biological Process mRNA 3'-splice site recognitionManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process mRNA cis splicing, via spliceosomeIEA:InterPro
Biological Process mRNA processingManual Assertion Based On ExperimentIMP:HGNC-UCL
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Nucleus speckle
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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