SF3A1

This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing.
Full Name
Splicing Factor 3a Subunit 1
Function
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex (PubMed:10882114, PubMed:11533230).
Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes (PubMed:29360106, PubMed:30315277).
Biological Process
Biological Process mRNA 3'-splice site recognitionManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process mRNA cis splicing, via spliceosomeIEA:InterPro
Biological Process mRNA processingManual Assertion Based On ExperimentIMP:HGNC-UCL
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Nucleus speckle
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Anti-SF3A1 antibodies

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Rabbit Anti-SF3A1 Recombinant Antibody (CBXS-1577) (CBMAB-S4426-CQ)

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Target: SF3A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1577
Application*: WB
Datasheet SDS

Rabbit Anti-SF3A1 Recombinant Antibody (CBXS-1576) (CBMAB-S4425-CQ)

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Target: SF3A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1576
Application*: WB, P
Datasheet SDS

Mouse Anti-SF3A1 Recombinant Antibody (CBXS-0966) (CBMAB-S3875-CQ)

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Target: SF3A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Mouse
Clone: CBXS-0966
Application*: IC, IP, WB
Datasheet SDS

Mouse Anti-SF3A1 Recombinant Antibody (CBXS-5290) (CBMAB-S2504-CQ)

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Target: SF3A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5290
Application*: P, WB
Datasheet SDS

Mouse Anti-SF3A1 Recombinant Antibody (CBXS-5266) (CBMAB-S2481-CQ)

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Target: SF3A1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5266
Application*: WB
Datasheet SDS

Mouse Anti-SF3A1 (AA 249-568) Recombinant Antibody (CBXS-4894) (CBMAB-S2116-CQ)

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Target: SF3A1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4894
Application*: P, WB
Datasheet SDS

Mouse Anti-SF3A1 Recombinant Antibody (CBXS-4441) (CBMAB-S1683-CQ)

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Target: SF3A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4441
Application*: P, WB
Datasheet SDS

Mouse Anti-SF3A1 Recombinant Antibody (CBXS-3879) (CBMAB-S1148-CQ)

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Target: SF3A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3879
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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