Mouse Anti-SFTPA1 Recombinant Antibody (3H2) (CBMAB-A8041-LY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
(Microbial infection) Recognition of M.tuberculosis by dendritic cells may occur partially via this molecule (PubMed:17158455, PubMed:21203928).
Can recognize, bind, and opsonize pathogens to enhance their elimination by alveolar macrophages (PubMed:21123169).3 Publications
(Microbial infection) Binds M.pneumoniae CARDS toxin, serves as one receptor for this pathogen (PubMed:15845487, PubMed:25139904).
When SFTPA1 is down-regulated by siRNA, less toxin binds to human cells and less vacuolization (a symptom of M.pneumoniae infection) is seen (PubMed:25139904).
Biological Process respiratory gaseous exchange by respiratory systemIEA:UniProtKB-KW
Secreted, extracellular space, extracellular matrix
Secreted, extracellular space, surface film
A form of interstitial lung disease, a heterogeneous group of diseases affecting the distal part of the lung and characterized by a progressive remodeling of the alveolar interstitium. The disease spectrum ranges from idiopathic interstitial pneumonia or pneumonitis to idiopathic pulmonary fibrosis, that is associated with an increased risk of developing lung cancer. Clinical features of interstitial lung disease include dyspnea, clubbing of the fingers, and restrictive lung capacity. ILD1 inheritance can be autosomal dominant with incomplete penetrance, and autosomal recessive.
Respiratory distress syndrome in premature infants (RDS):
A lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
SFTPA1 Matched Antibody Pair (1076) (CAT#: APMAB-1076LY)
SFTPA1 Matched Antibody Pair (1078) (CAT#: APMAB-1078LY)
SFTPA1 Matched Antibody Pair (1079) (CAT#: APMAB-1079LY)
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Mouse Anti-SFTPA1 Recombinant Antibody (4D6) (CAT#: CBMAB-A8043-LY)
SFTPA1 Matched Antibody Pair (1077) (CAT#: APMAB-1077LY)
Mouse Anti-SFTPA1 Recombinant Antibody (4C4) (CAT#: CBMAB-A8042-LY)
Mouse Anti-SFTPA1 Recombinant Antibody (CBYC-P835) (CAT#: CBMAB-P3664-YC)
Mouse Anti-SFTPA1 Recombinant Antibody (CBYC-P836) (CAT#: CBMAB-P3665-YC)
SFTPA1 Matched Antibody Pair (1076) (CAT#: APMAB-1076LY)
SFTPA1 Matched Antibody Pair (1078) (CAT#: APMAB-1078LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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