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Mouse Anti-TNFRSF1B Monoclonal Antibody (MR2-1) (CBMAB-1649-YC)

Provided herein is a mouse monoclonal antibody against Human TNFRSF1B. The antibody, clone MR2-1, can be used for immunoassay techniques, such as FC, ICC, IF, IP and WB.
Host Species
Mouse
Application
FC, ICC, IF, IP, WB
Immunogen
Soluble TNF-R75 from culture supernatant of cells transfected with the extracellular part of TNF-R75.
Antibody Isotype
IgG1
Specificity
Human, Cynomolgus, Monkey
Clone
MR2-1
Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
TNFRSF1B is a member of the TNF-receptor superfamily. TNFRSF1B and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. Knockout studies in mice also suggest a role of TNFRSF1B in protecting neurons from apoptosis by stimulating antioxidative pathways.
Alternative Name
p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-1649-YC
Conjugates
Size
Price $
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Second antibody and isotype control