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Mouse Anti-TP53 Monoclonal Antibody (1D9) (CBMAB-0265-LY)

This product is mouse monoclonal antibody recognizes TP53 of human. The antibody 1D9 immunoassay techniques such as: MA, WB.
Host Species
Mouse
Application
MA, WB
Immunogen
Recombinant peptide (Full Length)
Antibody Isotype
IgG2b
Specificity
Human
Clone
1D9
Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
Alternative Name
p53; LFS1
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0265-LY
Conjugates
Size
Price $
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Second antibody and isotype control