BAMBI(NMA), BMP-2, BMP-4, BMP-5, BMP-6, BMP-7, BMP-8, BMP-9, BMPR-IA(ALK-3), ALK-6(BMPR-IB), BMPR-II, COCO, Crossveinless-2(CV-2/BMPER), Follistatin, GDF-11(BMP-11), GDF-8(Myostatin)
Cell culture supernatants, Cell lysates, Plasma, Serum and Tissue lysates
Multiplexed Protein Detection
Block the array membrane surface
Incubate with Sample
Incubate with Biotinylated Detection Antibody Cocktail
Incubate with HRP Conjugated Streptavidin
Incubate with Detection Buffers
Image with chemiluminescent imaging system
Antibody Array Membrane
Store at -20°C for 6 months. Once thawed, please keep reagents under suitable conditions respectively for no more than 3 months. Do not use past expiration date.
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. The important functioning of BMP signals in physiology is emphasized by the multitude of roles for dysregulated BMP signalling in pathological processes. Cancerous disease often involves misregulation of the BMP signalling system. Absence of BMP signalling is, for instance, an important factor in the progression of colon cancer, and conversely, overactivation of BMP signalling following reflux-induced esophagitis provokes Barrett's esophagus and is thus instrumental in the development of adenocarcinoma in the proximal portion of the gastrointestinal tract.