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COMMD1 Matched Antibody Pair (288) (APMAB-288LY)

This antibody pair set can be used for detecting and quantifying protein level of human COMMD1.
See all COMMD1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-COMMD1 polyclonal antibody, 100 ug
Detection Antibody
Anti-COMMD1 Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
COMMD1 (Copper Metabolism Domain Containing 1) is a Protein Coding gene. Diseases associated with COMMD1 include Wilson Disease and Menkes Disease. Among its related pathways are Delta508-CFTR traffic / ER-to-Golgi in CF and Regulation of CFTR activity (norm and CF). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and copper ion binding.
Alternative Names
Copper Metabolism Domain Containing 1; Copper Metabolism (Murr1) Domain Containing 1; Copper Metabolism Gene MURR1; Protein Murr1; C2orf5; MURR1; Chromosome 2 Open Reading Frame 5 (MURR1); COMM Domain-Containing Protein 1; COMM Domain Containing 1;
Entrez Gene ID
150684
UniProt ID
Q8N668

Corbee, R. J., & Penning, L. C. (2021). COMMD1 Exemplifies the Power of Inbred Dogs to Dissect Genetic Causes of Rare Copper-Related Disorders. Animals, 11(3), 601.

Weiskirchen, R., & Penning, L. C. (2021). COMMD1, a multi-potent intracellular protein involved in copper homeostasis, protein trafficking, inflammation, and cancer. Journal of Trace Elements in Medicine and Biology, 65, 126712.

Li, C., Wang, T., Xiao, Y., Li, K., Meng, X., & James Kang, Y. (2021). COMMD1 upregulation is involved in copper efflux from ischemic hearts. Experimental Biology and Medicine, 246(5), 607-616.

Jiang, Z., Chen, W., Zhou, J., Peng, Q., Zheng, H., Yuan, Y., ... & Liu, X. (2019). Identification of COMMD1 as a novel lamin A binding partner. Molecular medicine reports, 20(2), 1790-1796.

Stewart, D. J., Short, K. K., Maniaci, B. N., & Burkhead, J. L. (2019). COMMD1 and PtdIns (4, 5) P2 interaction maintain ATP7B copper transporter trafficking fidelity in HepG2 cells. Journal of cell science, 132(19), jcs231753.

Jiang, Z., Yuan, Y., Zheng, H., Cui, H., Sun, X., Zhao, W., & Liu, X. (2019). COMMD1 regulates cell proliferation and cell cycle progression by modulating p21 Cip1 levels. Bioscience, Biotechnology, and Biochemistry, 83(5), 845-850.

Li, K., Li, C., Xiao, Y., Wang, T., & James Kang, Y. (2018). Featured Article: The loss of copper is associated with the increase in copper metabolism MURR domain 1 in ischemic hearts of mice. Experimental Biology and Medicine, 243(9), 780-785.

Riera‐Romo, M. (2018). COMMD1: a multifunctional regulatory protein. Journal of Cellular Biochemistry, 119(1), 34-51.

Fedoseienko, A., Wijers, M., Wolters, J. C., Dekker, D., Smit, M., Huijkman, N., ... & Van De Sluis, B. (2018). The COMMD family regulates plasma LDL levels and attenuates atherosclerosis through stabilizing the CCC complex in endosomal LDLR trafficking. Circulation research, 122(12), 1648-1660.

Mu, P., Akashi, T., Lu, F., Kishida, S., & Kadomatsu, K. (2017). A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma. Oncogene, 36(41), 5745-5756.

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For research use only. Not intended for any clinical use.

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