MCAT Matched Antibody Pair (722) (APMAB-722LY)

This antibody pair set can be used for detecting and quantifying protein level of human MCAT.
See all MCAT antibodies

Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-MCAT polyclonal antibody, 100 ug

Detection Antibody

Anti-MCAT Mouse polyclonal antibody, 40 ul

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]

Alternative Names

Malonyl-CoA-Acyl Carrier Protein Transacylase; Malonyl CoA:ACP Acyltransferase (Mitochondrial); Mitochondrial Malonyl CoA:ACP Acyltransferase; [Acyl-Carrier-Protein] S-Malonyltransferase; [Acyl-Carrier-Protein] Malonyltransferase; Mitochondrial Malonyltransferase; MCT; MT;

Entrez Gene ID

27349

UniProt ID

Q8IVS2

References

Webb, B. D., Nowinski, S. M., Solmonson, A., Ganesh, J., Rodenburg, R. J., Leandro, J., ... & Houten, S. M. (2023). Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency. Elife, 12, e68047.

Gerber, S., Orssaud, C., Kaplan, J., Johansson, C., & Rozet, J. M. (2021). MCAT mutations cause nuclear LHON-like optic neuropathy. Genes, 12(4), 521.

Li, H., Yuan, S., Minegishi, Y., Suga, A., Yoshitake, K., Sheng, X., ... & Iwata, T. (2020). Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy. Human molecular genetics, 29(3), 444-458.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-MCAT Recombinant Antibody (CBF31)

Mouse Anti-MCAT (AA 291-391) Recombinant Antibody (CBFYM-1860)

Mouse Anti-MCAT (AA 291-391) Recombinant Antibody (CBFYM-0481)

Rabbit Anti-MCAT (N-terminus) Recombinant Antibody (CBFYM-1859)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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