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Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (V2-7687) (CBMAB-1859CQ)


See all 8-hydroxy-deoxyguanosine antibodies
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Published Data
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IHC
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IHC
Representative immunohistochemical staining of 8-OHdG in the ventral horn segment of the spinal cord after sciatic nerve crush injury. 8-OHdG positive neurons were identified with brown nuclei among all experimental groups (Magnification ×40 and 100x). ...View More
Al-Arbeed, T. A., Renno, W. M., & Al-Hassan, J. M. (2023). Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage. Frontiers in Pharmacology, 14, 1085314.
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IHC
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IHC
Immunohistological expression of the DNA oxidation marker 8-hydroxy-2'-deoxyguanosine (8-OHdG) in age-matched moderate drinking control (CON) and alcohol use disorder (AUD) post-mortem human orbitofrontal cortex (OFC). Representative photomicrographs depicting the extent of 8-OHdG immunoreactivity in the OFC of individuals with AUD relative to moderate drinking CONs. Scale bar = 30 μm. ...View More
Qin, L., Vetreno, R. P., & Crews, F. T. (2023). NADPH oxidase and endoplasmic reticulum stress is associated with neuronal degeneration in orbitofrontal cortex of individuals with alcohol use disorder. Addiction Biology, 28(1), e13262.
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IF
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IF
Representative IF staining against 8-OHdG in testis, caput epididymis and cauda epididymis tissue sections from Prm1+/+, Prm1+/− and Prm1−/− males. ...View More
Merges, G. E., Meier, J., Schneider, S., Kruse, A., Fröbius, A. C., Kirfel, G., ... & Schorle, H. (2022). Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice. Development, 149(12), dev200330.
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IF
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IF
Assessment of 8-Oxo-2'-deoxyguanosine (8-OHdG), a market of oxidative stress, in skeletal muscle after 3 days of remobilization with PBS, mobile PC and Immobile PC treatment. ...View More
Wu, Y. F., De La Toba, E. A., Dvoretskiy, S., Jung, R., Kim, N., Daniels, L., ... & Boppart, M. D. (2022). Development of a cell-free strategy to recover aged skeletal muscle after disuse. The Journal of physiology.
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IHC
Mouse Anti-8-hydroxy-deoxyguanosine Recombinant Antibody (200) in IHC
Immunocytochemical visualization of stained reaction with antibodies against (a) MTCO-1 (Cytochrome c oxidase subunit I) and (b) 8-OHdG (8-hydroxy-2'-deoxyguanosine) in human gastric cancer cells sensitive (EPF85-237 P) and chemoresistant (EPF85-237 RDB) after the 72 h exposure to normal (NG) and altered gravity (MG) with doxorubicin (DOX = 0.5 ng/mL). Scale bars correspond to 50µm. ...View More
Rembiałkowska, N., Baczyńska, D., Dubińska-Magiera, M., Choromańska, A., Bieżuńska-Kusiak, K., Gajewska-Naryniecka, A., ... & Kulbacka, J. (2022). RCCS bioreactor-based modeled microgravity affects gastric cancer cells and improves the chemotherapeutic effect. Membranes, 12(5), 448.

Summary

Host Animal
Mouse
Clone
V2-7687
Antibody Isotype
IgG2b
Application
ELISA, IHC, ICC

Basic Information

Immunogen
8-oxo-dG-conjugated-KLH
Host Species
Mouse
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
8-hydroxy-deoxyguanosine
Introduction
8-hydroxy-deoxyguanosine (8-OHdG) is a sensitive marker of the DNA damage due to hydroxyl radical attack at the C8 of guanine. This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.
Alternative Names
8-Hydroxy-2'-deoxyguanosine; 8-Oxo-dG; 88847-89-6; 8-Hydroxydeoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7-hydrodeoxyguanosine
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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