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AFM

This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream. [provided by RefSeq, Jul 2008]
Full Name
Afamin
Function
Functions as carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier.
Biological Process
Protein stabilization
Protein transport within extracellular region
Vitamin transport
Cellular Location
Secreted
PTM
N-glycosylated; more than 90% of the glycans are sialylated.
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Anti-AFM antibodies

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Mouse Anti-AFM Recombinant Antibody (V2-634159) (CBMAB-AP185LY)

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Target: AFM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-634159
Application*: ELISA, IF, IP, WB
Datasheet SDS

Mouse Anti-AFM Recombinant Antibody (V2-180060) (CBMAB-A1470-YC)

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Target: AFM
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-180060
Application*: WB, IC, P, E
Datasheet SDS

Mouse Anti-AFM Recombinant Antibody (V2-180059) (CBMAB-A1469-YC)

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Target: AFM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-180059
Application*: WB
Datasheet SDS

Mouse Anti-AFM Recombinant Antibody (V2-180057) (CBMAB-A1467-YC)

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Target: AFM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: V2-180057
Application*: E, WB, IP, IH, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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