BTN1A1
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families.
Full Name
Butyrophilin Subfamily 1 Member A1
Function
May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity).
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity).
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity).
Biological Process
Adaptive immune response Source: Reactome
Regulation of cytokine production Source: GO_Central
T cell receptor signaling pathway Source: GO_Central
Regulation of cytokine production Source: GO_Central
T cell receptor signaling pathway Source: GO_Central
Cellular Location
Secreted; Membrane
Topology
Extracellular: 27-242 aa
Helical: 243-269 aa
Cytoplasmic: 270-526 aa
Helical: 243-269 aa
Cytoplasmic: 270-526 aa
PTM
N-glycosylated.
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Anti-BTN1A1 antibodies
+ Filters

Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2175
Application*: WB, F
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBT4056
Application*: WB, F
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1960
Application*: WB, IF, FC
Target: BTN1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-0919
Application*: FC, IF
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0909
Application*: WB, IF
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Rat, Monkey
Clone: CBYY-0908
Application*: IF, WB
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Rat, Monkey
Clone: CBYY-0907
Application*: FC, IF, WB, IH
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0906
Application*: WB, IF, FC
Target: BTN1A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBYY-0905
Application*: WB, E, FC
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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