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Ccrl2

CCRL2 (C-C Motif Chemokine Receptor Like 2) is a Protein Coding gene. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor binding.
Full Name
C-C Motif Chemokine Receptor Like 2
Function
Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.
Biological Process
Calcium-mediated signaling Source: GO_Central
Cell chemotaxis Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: ProtInc
Immune response Source: GO_Central
Inflammatory response Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-43
Helical: 44-64
Cytoplasmic: 65-74
Helical: 75-95
Extracellular: 96-104
Helical: 105-125
Cytoplasmic: 126-144
Helical: 145-165
Extracellular: 166-198
Helical: 199-219
Cytoplasmic: 220-238
Helical: 239-259
Extracellular: 260-286
Helical: 287-307
Cytoplasmic: 308-344
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Anti-Ccrl2 antibodies

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Mouse Anti-CCRL2 Recombinant Antibody (CBT4780) (V2LY-0625-LY1673)

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Target: CCRL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4780
Application*: F
Datasheet SDS

Rabbit Anti-CCRL2 Recombinant Antibody (EG525) (CBMAB-EN598-LY)

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Target: CCRL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: EG525
Application*: E, WB, IF, F, IH, IP
Datasheet SDS

Mouse Anti-CCRL2 Recombinant Antibody (CBXC-2603) (CBMAB-C0908-CQ)

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Target: CCRL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-2603
Application*: IH, WB
Datasheet SDS

Mouse Anti-CCRL2 Recombinant Antibody (CBFYC-1091) (CBMAB-C1148-FY)

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Target: CCRL2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1091
Application*: IH, WB
Datasheet SDS

Mouse Anti-CCRL2 Recombinant Antibody (CBFYC-0255) (CBMAB-C0285-FY)

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Target: CCRL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0255
Application*: E, WB, IF, F
Datasheet SDS

Rat Anti-CCRL2 Recombinant Antibody (498321) (CBMAB-C1365-LY)

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Target: CCRL2
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 498321
Application*: F, IC
Datasheet SDS

Mouse Anti-CCRL2 Recombinant Antibody (5A15) (CBMAB-C7261-LY)

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Target: CCRL2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 5A15
Application*: F
Datasheet SDS

Mouse Anti-CCRL2 Recombinant Antibody (152211) (CBMAB-C0353-LY)

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Target: CCRL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 152211
Application*: F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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