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CD101

CD101 (CD101 Molecule) is a Protein Coding gene. Diseases associated with CD101 include Langerhans Cell Histiocytosis and Histiocytosis. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. An important paralog of this gene is IGSF3.
Full Name
CD101 Molecule
Function
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4+ CD56+ leukemic tumor cells.
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Positive regulation of myeloid leukocyte differentiation Source: Ensembl
Cellular Location
Membrane
Topology
Extracellular: 21-954
Helical: 955-975
Cytoplasmic: 976-1021
PTM
N-glycosylated.
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Anti-CD101 antibodies

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Mouse Anti-CD101 Recombinant Antibody (BB27) (CBMAB-AP928LY)

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Target: CD101
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BB27
Application*: F, IP, IH
Datasheet SDS

Mouse Anti-CD101 Recombinant Antibody (CBT2885) (V2LY-0625-LY1223)

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Target: CD101
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2885
Application*: WB
Datasheet SDS

Mouse Anti-CD101 Recombinant Antibody (CBT3446) (V2LY-0625-LY1124)

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Target: CD101
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3446
Application*: F
Datasheet SDS

Mouse Anti-CD101 Recombinant Antibody (CBYY-C2749) (CBMAB-C4190-YY)

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Target: CD101
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2749
Application*: WB, E
Datasheet SDS

Rat Anti-CD101 Recombinant Antibody (CBYY-C0653) (CBMAB-C1944-YY)

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Target: CD101
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C0653
Application*: F
Datasheet SDS

Mouse Anti-CD101 Recombinant Antibody (CBYY-I0852) (CBMAB-I1968-YY)

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Target: CD101
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0852
Application*: WB, E, F
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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