COL10A1

COL10A1 (Collagen Type X Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL10A1 include Metaphyseal Chondrodysplasia, Schmid Type and Cartilage-Hair Hypoplasia. Among its related pathways are Integrin Pathway and ERK Signaling. An important paralog of this gene is COL8A2.
Full Name
Collagen Type X Alpha 1 Chain
Function
Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
Biological Process
Collagen fibril organization Source: Reactome
Extracellular matrix organization Source: GO_Central
Skeletal system development Source: ProtInc
Cellular Location
Extracellular matrix
Involvement in disease
Schmid type metaphyseal chondrodysplasia (SMCD):
Dominantly inherited disorder of the osseous skeleton. The cardinal features of the phenotype are mild short stature, coxa vara and a waddling gait. Radiography usually shows sclerosis of the ribs, flaring of the metaphyses, and a wide irregular growth plate, especially of the knees. A variant form of SMCD is spondylometaphyseal dysplasia Japanese type. It is characterized by spinal involvement comprising mild platyspondyly, vertebral body abnormalities, and end-plate irregularity.
PTM
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
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Anti-COL10A1 antibodies

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Rabbit Anti-COL10A1 Recombinant Antibody (C11093) (V2LY-1206-LY588)

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Target: COL10A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: C11093
Application*: WB
Datasheet SDS

Mouse Anti-COL10A1 Recombinant Antibody (CBCNC-059) (V2LY-1206-LY587)

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Target: COL10A1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Dog, Guinea pig, Human, Mouse, Pig, Rat
Clone: CBCNC-059
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-COL10A1 Recombinant Antibody (CBWJC-2906) (V2LY-1206-LY586)

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Target: COL10A1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Chicken
Clone: CBWJC-2906
Application*: P, IF
Datasheet SDS

Mouse Anti-COL10A1 Recombinant Antibody (CBXC-0503) (V2LY-1206-LY585)

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Target: COL10A1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Chicken
Clone: CBXC-0503
Application*: IF, WB, P
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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