CRABP2

CRABP2 (Cellular Retinoic Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with CRABP2 include Embryonal Carcinoma and Basal Cell Carcinoma. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include transporter activity and retinol binding. An important paralog of this gene is CRABP1.
Full Name
Cellular Retinoic Acid Binding Protein 2
Function
Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
Biological Process
Embryonic forelimb morphogenesis Source: Ensembl
Epidermis development Source: ProtInc
Positive regulation of collateral sprouting Source: Ensembl
Regulation of transcription, DNA-templated Source: ProtInc
Retinoic acid metabolic process Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Cytoplasm; Nucleus; Endoplasmic reticulum. Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.
PTM
Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation.
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Anti-CRABP2 antibodies

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Target: CRABP2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat, Pig
Clone: CBFYC-2181
Application*: WB, IF, IH
Target: CRABP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Pig
Clone: CBFYC-0423
Application*: WB, IF, IH
Target: CRABP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0056
Application*: F, IF
Target: CRABP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F2
Application*: E, WB, IF
Target: CRABP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 016
Application*: E
Target: CRABP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 01
Application*: WB, E
Target: CRABP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 4
Application*: WB
Target: CRABP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 2E11
Application*: WB, F, IF, E
Target: CRABP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 05
Application*: P
Target: CRABP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 004
Application*: WB, F, IF, IP
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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