GRIK4

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Full Name
glutamate ionotropic receptor kainate type subunit 4
Function
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
Biological Process
Chemical synaptic transmission Source: ProtInc
Glutamate receptor signaling pathway Source: ProtInc
Modulation of chemical synaptic transmission Source: GO_Central
Synaptic transmission, glutamatergic Source: GO_Central
Cellular Location
Cell membrane; Postsynaptic cell membrane
Topology
Extracellular: 21-545
Helical: 546-566
Cytoplasmic: 567-623
Helical: 624-644
Extracellular: 645-804
Helical: 805-825
Cytoplasmic: 826-956
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Anti-GRIK4 antibodies

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Mouse Anti-GRIK4 Recombinant Antibody (CBT2011) (V2LY-0625-LY740)

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Target: GRIK4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2011
Application*: IH, IC, F
Datasheet SDS

Mouse Anti-GRIK4 Recombinant Antibody (CBT4460) (V2LY-0625-LY739)

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Target: GRIK4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT4460
Application*: IH, IC, F
Datasheet SDS

Rabbit Anti-GRIK4 Recombinant Antibody (CBLY1-029) (CBMAB-K0350-LY)

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Target: GRIK4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLY1-029
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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