GTF3A

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Full Name
General Transcription Factor IIIA
Function
Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes (PubMed:24120868).

Also binds the transcribed 5S RNA's (By similarity).
Biological Process
Ribosomal large subunit biogenesis Source: UniProtKB
rRNA transcription Source: ProtInc
Transcription by RNA polymerase III Source: ProtInc
Cellular Location
Nucleus
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Anti-GTF3A antibodies

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Mouse Anti-GTF3A Recombinant Antibody (CBLG1-2129) (CBMAB-G5737-LY)

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Target: GTF3A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-2129
Application*: SE, E, WB
Datasheet SDS

Mouse Anti-GTF3A Recombinant Antibody (1C6) (CBMAB-G5732-LY)

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Target: GTF3A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1C6
Application*: E, WB
Datasheet SDS

Rabbit Anti-GTF3A Recombinant Antibody (EG1467) (CBMAB-EN1753-LY)

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Target: GTF3A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1467
Application*: WB: 1:500~1:3000 ELISA: 1:40000
Datasheet SDS

Mouse Anti-GTF3A Recombinant Antibody (CBFYH-0536) (CBMAB-H1416-FY)

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Target: GTF3A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYH-0536
Application*: E, EC, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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