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Rabbit Anti-GTF3A Recombinant Antibody (EG1467) (CBMAB-EN1753-LY)

The product is antibody recognizes GTF3A. The antibody EG1467 immunoassay techniques such as: WB: 1:500~1:3000 ELISA: 1:40000.
See all GTF3A antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1467
Antibody Isotype
IgG
Application
WB: 1:500~1:3000 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from Internal of human GTF3A.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
General Transcription Factor IIIA
Introduction
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Entrez Gene ID
2971
UniProt ID
Q92664
Alternative Names
General Transcription Factor IIIA; TFIIIA; Transcription Factor IIIA; AP2;
Function
Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes (PubMed:24120868).

Also binds the transcribed 5S RNA's (By similarity).
Biological Process
Ribosomal large subunit biogenesis Source: UniProtKB
rRNA transcription Source: ProtInc
Transcription by RNA polymerase III Source: ProtInc
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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