KRT9

This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008]

Full Name

Keratin 9

Function

May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.

Biological Process

Epidermis developmentManual Assertion Based On ExperimentTAS:ProtInc
Intermediate filament organizationManual Assertion Based On ExperimentIMP:UniProtKB
Skin developmentManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:Ensembl

Cellular Location

Cytosol
Extracellular exosome
Extracellular space
Intermediate filament
Membrane
Nucleus

Involvement in disease

Keratoderma, palmoplantar, epidermolytic (EPPK):
A dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present knuckle pads, thick pads of skin appearing over the proximal phalangeal joints.

Anti-KRT9 antibodies

Mouse Anti-KRT9 Recombinant Antibody (Ks9.70 + Ks9.216) (CBMAB-C5444WJ)

Datasheet

SDS

Target: KRT9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: Ks9.70 + Ks9.216

Application*: P, IF, WB

Mouse Anti-KRT9 Recombinant Antibody (16k94) (CBMAB-C3397-LY)

Datasheet

SDS

Target: KRT9

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: 16k94

Application*: IF, C, WB

Mouse Anti-KRT9 Recombinant Antibody (K9.70/Ks9.216) (CBMAB-K2051-LY)

Datasheet

SDS

Target: KRT9

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: K9.70/Ks9.216

Application*: IF, C, P, WB

Mouse Anti-KRT9 Recombinant Antibody (AE1) (CBMAB-K2050-LY)

Datasheet

SDS

Target: KRT9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: AE1

Application*: C, P

Mouse Anti-KRT9 Recombinant Antibody (A849) (CBMAB-AP4108LY)

Datasheet

SDS

Target: KRT9

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: A849

Application*: ICC, IHC, IP, WB

Mouse Anti-KRT9 Recombinant Antibody (5F236) (CBMAB-C3900-CN)

Datasheet

SDS

Target: KRT9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 5F236

Application*: IF, IH, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)