KRT9
This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008]
Full Name
Keratin 9
Function
May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.
Biological Process
Epidermis developmentManual Assertion Based On ExperimentTAS:ProtInc
Intermediate filament organizationManual Assertion Based On ExperimentIMP:UniProtKB
Skin developmentManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:Ensembl
Intermediate filament organizationManual Assertion Based On ExperimentIMP:UniProtKB
Skin developmentManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:Ensembl
Cellular Location
Cytosol
Extracellular exosome
Extracellular space
Intermediate filament
Membrane
Nucleus
Extracellular exosome
Extracellular space
Intermediate filament
Membrane
Nucleus
Involvement in disease
Keratoderma, palmoplantar, epidermolytic (EPPK):
A dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present knuckle pads, thick pads of skin appearing over the proximal phalangeal joints.
A dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present knuckle pads, thick pads of skin appearing over the proximal phalangeal joints.
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Anti-KRT9 antibodies
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Target: KRT9
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A849
Application*: ICC, IHC, IP, WB
Target: KRT9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 5F236
Application*: IF, IH, WB
Target: KRT9
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: 16k94
Application*: IF, C, WB
Target: KRT9
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: K9.70/Ks9.216
Application*: IF, C, P, WB
Target: KRT9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AE1
Application*: C, P
Target: KRT9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT4215
Application*: WB, F
Target: KRT9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT3928
Application*: WB, F
Target: KRT9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2581
Application*: WB, IH, F
Target: KRT9
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: Ks9.70 + Ks9.216
Application*: P, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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