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MCAM

MCAM (Melanoma Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with MCAM include Melanoma and Melanoma Metastasis. Among its related pathways are Adhesion. An important paralog of this gene is BCAM.
Full Name
Melanoma Cell Adhesion Molecule
Function
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Biological Process
Anatomical structure morphogenesis Source: ProtInc
Angiogenesis Source: MGI
Cell adhesion Source: ProtInc
Glomerular filtration Source: UniProtKB
Positive regulation of cell migration Source: Ensembl
Vascular wound healing Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 24-559
Helical: 560-583
Cytoplasmic: 584-646

Anti-MCAM antibodies

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Target: MCAM
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYA-0135
Application*: C, IF, IP, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0134
Application*: C
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4142
Application*: IC, IF, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0088
Application*: F, IP
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-0015
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0014
Application*: F
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBFYM-1858
Application*: IF, C, WB, IP, P, IC, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-1857
Application*: E, WB, IH, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-4138
Application*: WB, IH
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4137
Application*: WB, IH
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-4135
Application*: P, IC, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Chicken
Clone: CBWJC-2326
Application*: C, IP, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: C146/634
Application*: F, IF, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: P1H12
Application*: F, IP, WB, IH, IC
Target: MCAM
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: ME-9F1
Application*: F
Target: MCAM
Host: Hamster
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-1856
Application*: F, IF, IH, IP, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2589
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2655
Application*: E, F, IH, WB
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-C2654
Application*: WB, P, IP
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2653
Application*: F, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: CBYY-C2652
Application*: F, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2651
Application*: E, F, IH
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C3F1
Application*: E, WB, P, IF, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0322
Application*: F
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2941
Application*: WB, E, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBFYM-0388
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0387
Application*: F, IH, IF, MC
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0381
Application*: F, IF, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Chicken
Clone: CBFYM-0248
Application*: F, IC
Target: MCAM
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYM-0203
Application*: E, F, IC
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: CBFYM-0142
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0037
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: MCAM/1101
Application*: F, P
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 044
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1/MCAM
Application*: WB, IF
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Chicken
Clone: c264
Application*: F, IH, C, IP, IC
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-1855
Application*: P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-1854
Application*: E, WB
Target: MCAM
Host: Mouse
Specificity: Human
Clone: CBFYM-1853
Application*: E, IP
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-1852
Application*: IH, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0601
Application*: IC, IH, IP, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0600
Application*: E, F, IC, IH, IP
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Chicken
Clone: CBFYM-0599
Application*: F, C, IP
Target: MCAM
Host: Mouse
Specificity: Human
Clone: CBFYM-0458
Application*: E
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1229
Application*: FC, IF
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1228
Application*: FC, IF, IHC
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 012
Application*: WB, E, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1227
Application*: FC, IF, IHC
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1226
Application*: FC, IF, IHC
Target: MCAM
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 733216
Application*: F, IC, B
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1231
Application*: FC, IF, IHC
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: SHM-57
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: N1238
Application*: WB, P
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: MUC18/1130
Application*: P, IF/IC, C
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM249
Application*: WB, IH
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 7H217
Application*: E, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3H6
Application*: WB, E
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A1230
Application*: FC, IF, IHC
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 01
Application*: F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 541-10B2
Application*: F
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 2H17L14
Application*: WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 68
Application*: ELISA, IHC, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 404722
Application*: C, WB
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CAP946
Application*: ELISA, FC, IF, IHC, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A36
Application*: E, F, C, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C3E6
Application*: E, WB, P, IF/C, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: OJ79c
Application*: F, IH, IF
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4H315
Application*: IF, IH, IP, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4D10C7
Application*: E, WB, IF, F
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBNH-017
Application*: E, WB, IH, IF, F
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF282
Application*: ELISA, WB, IHC, FC
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rabbit
Clone: 2Q401
Application*: E, F, IC, IH, IP
Target: MCAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 44
Application*: E
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2E2F4D5
Application*: E, IP
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B8C5D8
Application*: E
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1869
Application*: E, F, IH
Target: MCAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4H55
Application*: C, WB
Target: MCAM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB22A
Application*: ELISA, WB, IF, FC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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