MMP23B

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]

Matrix Metallopeptidase 23B

Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).

Collagen catabolic process Source: GO_Central
Extracellular matrix organization Source: GO_Central
Proteolysis Source: UniProtKB
Reproduction Source: UniProtKB

Endoplasmic reticulum
Endoplasmic reticulum membrane
Other locations
Membrane
Note: A secreted form produced by proteolytic cleavage may also exist.

Cytoplasmic: 1-19
Helical: 20-40
Lumenal: 41-390

N-glycosylated.
Proteolytic cleavage might yield an active form.