NELL1

This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Full Name
Neural EGFL Like 1
Function
Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization.
Biological Process
Cell differentiation Source: UniProtKB-KW
Negative regulation of cellular protein catabolic process Source: UniProtKB
Negative regulation of osteoblast proliferation Source: UniProtKB
Nervous system development Source: ProtInc
Positive regulation of bone mineralization Source: UniProtKB
Positive regulation of osteoblast differentiation Source: UniProtKB
Regulation of gene expression Source: UniProtKB
Cellular Location
Nucleus
Nucleus envelope
Cytoplasm
Secreted
Note: Colocalizes with ATRAID on the nuclear envelope and the perinuclear region.
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Anti-NELL1 antibodies

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Mouse Anti-NELL1 Recombinant Antibody (CBWJN-0506) (CBMAB-N1960-WJ)

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Target: NELL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-0506
Application*: E, WB
Datasheet SDS

Mouse Anti-NELL1 Recombinant Antibody (6A8) (CBMAB-N1959-WJ)

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Target: NELL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6A8
Application*: E, IF, IP, WB
Datasheet SDS

Mouse Anti-NELL1 Recombinant Antibody (3F1) (CBMAB-N1958-WJ)

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Target: NELL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F1
Application*: E
Datasheet SDS

Mouse Anti-NELL1 Recombinant Antibody (CBWJN-1324) (CBMAB-N1955-WJ)

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Target: NELL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1324
Application*: WB
Datasheet SDS

Mouse Anti-NELL1 Recombinant Antibody (CBWJN-1323) (CBMAB-N1954-WJ)

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Target: NELL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1323
Application*: IC
Datasheet SDS

Human NELL1 ELISA Kit (V2LY-0626-LY5104)

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Target: NELL1
Sensitivity: 0.0097 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Nell1 ELISA Kit (V2LY-0626-LY2929)

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Target: Nell1
Sensitivity: 0.019 ng/mL
Detection Range: 0.05-20 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

NELL1 Matched Antibody Pair (792) (APMAB-792LY)

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Target: NELL1
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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