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NUDT10

NUDT10 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM

Full Name

nudix (nucleoside diphosphate linked moiety X)-type motif 10

Function

Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.

Biological Process

Adenosine 5'-(hexahydrogen pentaphosphate) catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Diadenosine hexaphosphate catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Diadenosine pentaphosphate catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Diphosphoinositol polyphosphate metabolic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm

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Anti-NUDT10 antibodies

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Mouse Anti-NUDT10 Recombinant Antibody (2G8) (CBMAB-N3871-WJ)

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Target: NUDT10

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2G8

Application*: WB

Mouse Anti-NUDT10 Recombinant Antibody (2F8) (CBMAB-N3870-WJ)

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Target: NUDT10

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2F8

Application*: E, WB

Mouse Anti-NUDT10 Recombinant Antibody (2B7) (CBMAB-N3868-WJ)

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Target: NUDT10

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2B7

Application*: WB

Mouse Anti-NUDT10 Recombinant Antibody (1A3) (CBMAB-N3865-WJ)

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Target: NUDT10

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A3

Application*: WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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